In this Windows 10 guide, we walk you through the easy steps to change the primary and secondary button actions of your mouse. However, if you're a left-handed person, or you want to switch hands after an extended period, you can use the Settings app and Control Panel to quickly change the mouse settings to reassign the left and right buttons to click, select, drag, and perform other actions using your left hand on Windows 10.

On Windows 10, when connecting a mouse to your computer, the system will usually set the left button as the primary key, as it's the default setting for any right-handed person.